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Course Code: 
MDD 310
Course Period: 
Autumn
Course Type: 
Core
P: 
2
Lab: 
1
Credits: 
2,5
ECTS: 
3
Course Language: 
English
Course Objectives: 
The aim of this course is to provide students with a thorough knowledge of general principles of pharmacology, antimicrobial drugs, autonomic system drugs, cardiovascular system drugs, central nervous system drugs, modulators of calcium metabolism and non-steroidal anti-inflammatory drugs with a special emphasis of their use in dentistry clinic.
Course Content: 

The course covers topics such as Introduction to the antimicrobial chemotherapeutics, Beta Lactam antibiotics, Vancomycin and other antimicrobial drugs, Macrolids, Quinolones, Sulfonamides, chloramphenicol and tetracyclines, Aminoglycosides, Antimycobacterial drugs, Antiviral drugs, Antiprotozoal drugs, Antifungal drugs, Antimalarial drugs, Antihelmintic drugs, Antiseptics and disinfectants, Pharmacology Of Renin Angiotensin System, Calcium Channel Blockers, Pharmacological Approach to Ischemic Heart Disease, Drugs Effecting Body Fluids & Volume, Anti-hypertensive Drugs, Hypolipidemic Drugs, Pharmacological Approach to Congestive Heart Disease, Antiarrhythmic Drugs, Bronchodilator Drugs, Antitussives, expectorants and surfactants, Antiplatelet Drugs, Antithrombotic and Thrombolytic drugs, Pharmacology and toxicology of tobacco, Prescription writing, Pharmacological basis of cancer therapy, Antineoplastic drugs.

Course Methodology: 
1: Lecture, 2: Question-Answer, 3: Discussion, 4: Practice
Course Evaluation Methods: 
A: Testing, B: lab study

Vertical Tabs

Course Learning Outcomes

 

Learning Outcomes 

By the end of the course, the student should; 

Programme learning outcomes Teaching Methods  Assessment Methods 
describe the concept of selective toxicity

describe the effects and mechanisms of action of a range of antibacterial and antiviral drugs.

list the problems associated with using chemotherapeutic agents, especially the risk of toxicity and resistance.

PLO 9,15 1, 2, 3, 4,  A, B
Beta Lactam antibiotics.

describe the mechanisms of action of this antibiotic group

list the sub groups and members of this antibiotic group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this antibiotic group related to toxicity and

resistance

PLO 9,15 1, 2, 3, 4,  A, B
Vancomycin and other antimicrobial drugs.

describe the mechanisms of action of this antibiotic group

list the sub groups and members of this antibiotic group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this antibiotic group related to toxicity and

resistance

PLO 9,15 1, 2, 3, 4,  A, B
Macrolids.

describe the mechanisms of action of this antibiotic group

list the sub groups and members of this antibiotic group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this antibiotic group related to toxicity and

resistance

PLO 9,15 1, 2, 3, 4,  A, B
Quinolones.

describe the mechanisms of action of this antibiotic group

list the sub groups and members of this antibiotic group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this antibiotic group related to toxicity and

resistance

PLO 9,15 1, 2, 3, 4,  A, B
Sulfonamides, chloramphenicol and tetracyclins.

describe the mechanisms of action of each antibiotic group

list the sub groups and members of this antibiotic group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with each antibiotic group related to toxicity and resistance

PLO 9,15 1, 2, 3, 4, A, B
Aminoglycosides.

describe the mechanisms of action of this antibiotic group

list the sub groups and members of this antibiotic group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this antibiotic group related to toxicity and resistance

PLO 9,15 1, 2, 3, 4, A, B
Antimycobacterial drugs.

describe the mechanisms of action of this antibiotic group

list the sub groups and members of this antibiotic group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this antibiotic group related to toxicity and resistance

PLO 9,15 1, 2, 3, 4, A, B
Antiviral drugs.

describe the mechanisms of action of this group

list the sub groups and members of this group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this group related to toxicity and resistance

PLO 9,15 1, 2, 3, 4, A, B
Antiprotozoal drugs.

describe the mechanisms of action of this group

list the sub groups and members of this group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this group related to toxicity and resistance

PLO 9,15 1, 2, 3, 4, A, B
Antifungal drugs.

describe the mechanisms of action of this group.

list the sub groups and members of this group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this group related to toxicity and resistance

PLO 9,15 1, 2, 3, 4, A, B
Antimalarial drugs.

describe the mechanisms of action of this group

list the sub groups and members of this group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this group related to toxicity and resistance

PLO 9,15 1, 2, 3, 4, A, B
Antihelmintic drugs.

describe the mechanisms of action of this group

list the sub groups and members of this group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this group related to toxicity and resistance

PLO 9,15 1, 2, 3, 4, A, B
Antiseptics and disinfectants.

describe the mechanisms of action of this group

list the sub groups and members of this group

list the antimicrobial spectrum

list the clinical uses

describe the problems associated with this group related to toxicity and resistance

PLO 9,15 1, 2, 3, 4, A, B
Pharmacology Of Renin Angiotensin System.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Calcium Channel Blockers.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Pharmacological Approach to Ischemic Heart Disease.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Drugs Effecting Body Fluids & Volume.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Anti-hypertensive Drugs.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Hypolipidemic Drugs.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Pharmacological Approach to Congestive Heart Disease.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Antiarrhythmic Drugs.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Bronchodilator Drugs.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Antitussives, expectorants and surfactants.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Antiplatelet Drugs.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Antithrombotic and Thrombolytic drugs.

describe the basic physiology and pathophysiology

describe the mechanisms of action of the drugs in this group

list the sub groups and members of the drugs in this group

list the clinical uses the drugs in this group

describe the problems associated with this group related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Pharmacology and toxicology of tobacco.

describe the basic physiology and pathophysiology

list the basic bioactive substances in tobacco

describe the mechanisms of action of the basic bioactive substances in tobacco

describe the problems associated with the bioactive substances related to toxicity

PLO 9,15 1, 2, 3, 4, A, B
Prescription writing.

describe the structure and the sections of the prescription

describe the terms including original drug, equivalent drug, brand name and genericname

write a complete prescription

list the factors to be considered while writing a prescription

PLO 9,15 1, 2, 3, 4, A, B
Pharmacological basis of cancer therapy.

describe the basic properties of cancer

describe the concepts of selective toxicity and log-­‐kill hypothesis in cancer therapy

list the effects and mechanisms of action of a range of anticancer drugs

list the problems associated with using chemotherapeutic agents, especially the risk of toxicity and resistance

PLO 9,15 1, 2, 3, 4, A, B
Antineoplastic drugs.

describe the mechanisms of action of antineoplastic drugs

list the sub groups and members

list the clinical uses

describe the problems associated with this group related to toxicity and resistance

PLO 9,15 1, 2, 3, 4, A, B

Course Flow

THEORETICAL COURSE CONTENT  *FALL

 

COURSE CONTENT (5th .semester)  
Week  Theoretical Topics                                       Study Materials
1 Introduction to the antimicrobial chemotherapeutics Recommended resources 
2 Beta Lactam antibiotics Recommended resources 
3 Vancomycin and other antimicrobial drugs Recommended resources 
4 Macrolids, Quinolones, Sulfonamides Recommended resources 
5 chloramphenicol and tetracyclines, Aminoglycosides Recommended resources 
6 Antimycobacterial drugs, Antiviral drugs Recommended resources 
7 Antiprotozoal drugs, Antifungal drugs Recommended resources 
8 Antimalarial drugs, Antihelmintic drugs Recommended resources 
9 Antiseptics and disinfectants Recommended resources 
10 Pharmacology Of Renin Angiotensin System Recommended resources 
11 Calcium Channel Blockers Recommended resources 
12 Pharmacological Approach to Ischemic Heart Disease Recommended resources 
13 Drugs Effecting Body Fluids & Volume Recommended resources 
14 General review Recommended resources 
       

 

PRACTICAL COURSE CONTENT  * FALL 

COURSE CONTENT (5th. semester)  
Week  Practical Topics                                       Study Materials
1 Lab studies  Study the sources. 
2 Lab studies  Study the sources.
3 Lab studies  Study the sources.
4 Lab studies  Study the sources.
5 Lab studies  Study the sources.
6 Lab studies Study the sources.
7 Lab studies Study the sources.
8 Lab studies Study the sources.
9 Lab studies Study the sources.
10 Lab studies Study the sources.
11 Lab studies Study the sources.
12 Lab studies Study the sources.
13 Lab studies Study the sources.
14 Lab studies Study the sources.

Recommended Sources

 

RECOMMENDED SOURCES
Textbook 1.John A. Yagiela, John A. Yagiela, Enid A. Neidle, Frank J. Dowd eds., Pharmacology and Therapeutics for Dentistry. Elsevier, Mosby. 6th ed. 2011.

B. G. Katzung: Basic and Clinical Pharmacology, 11th ed. McGraw-­‐Hill Companies, New York, 2009.

2.Goodman&Gilman’s The Pharmacologic Basis of Therapeutics, 12th ed.McGraw Hill Medical, 2011

 

Additional Resources

- Lecture notes

 

Material Sharing

 

MATERIAL SHARING
Documents Photocopy shareable.
Assignments Sharable.
Exams Not shareable.

Assessment

 

ASSESSMENT
IN-TERM STUDIES NUMBER PERCENTAGE
Midterm Exam 1 50
Quiz - -
Homework - -
Total   50
CONTRIBUTION OF FINAL EXAMINATION TO OVERALL GRADE   50
CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE   50
Total   100

Course’s Contribution to Program

 

COURSE'S CONTRIBUTION TO PROGRAM
No Program Learning Outcomes Contribution
1 2 3 4 5  
9 Integrating basic medical sciences in clinical sciences and using this information in all procedures of the patient.         X  
15 Following international literature, evaluating publications critically and integration of research results and evidence based dentistry during practice.         X  

ECTS

 

Activity  NUMBER  Duration
(Hours )
Total workload
(Hours )
Course duration  1st semester   ( theoretical)  14 2 28
Course duration  2nd semester   ( theoretical) 14 2 28
Course duration  1st semester   ( practical ) 14 1 14
Course duration  2nd semester   ( practical ) 14 1 14
Studies outside the class  ( 1st semester )  14 4.5 63
TOTAL      147
Total workload /25     5.8
ECTS credits of the course      6